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IM-156(acetate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IM-156(acetate)图片
CAS NO:2043654-54-0
包装:200 mg
市场价:7091元

产品名称
IM-156 (acetate)
产品介绍

产品描述

IM-156 is an inhibitor of mitochondrial complex I, also known as NADH dehydrogenase (IC50= 2.2 μM) and an activator of AMP-activated protein kinase α (AMPKα).1,2It reduces the oxygen consumption rate (OCR; IC50= 3.3 μM) and decreases mitochondrial ATP production in Eμ-Mycmouse lymphoma cells.1IM-156 (10, 30, and 50 μM) increases AMPKα activity in primary rat peritoneal mesothelial cells and protects against chlorhexidine-induced peritoneal fibrosis in rats when administered at a dose of 1 mg/kg.2It reduces tumor growth in an AT-84 murine oral cancer model and decreases age-related decline in novel object recognition, spatial working, and contextual memory in mice.3,4

Cas No.

2043654-54-0

分子式

C13H16F3N5O·XC2H4O2

分子量

315.3

别名

IM-156 (acetate)

储存和溶解度

DMF:1 mg/mL
DMSO:1 mg/mL
Ethanol:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years