Delpazolid 是一种恶唑烷酮类新型抗生素,能抑制MSSA和MRSA的生长,对它们的MIC90值都为 2 μg/mL。
产品描述
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
Cas No.
1219707-39-7
分子式
C14H17FN4O3
分子量
308.313
别名
LCB01-0371;Delpazolid
储存和溶解度
DMSO:30 mg/mL (97.30 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years