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Ceftobiprole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ceftobiprole图片
CAS NO:209467-52-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
Ro 63-9141
BAL 9141
头孢吡普
产品介绍
Ceftobiprole是一种广谱头孢菌素,对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。

产品描述

Ceftobiprole is a broad-spectrum cephalosporin with activity against Methicillin-resistant staphylococcus aureus (MRSA; MIC90: 2 μg/mL).

体外活性

Ceftobiprole has demonstrated activity against important gram-positive bacteria, including penicillin-resistant S. pneumonia (PRSP), Methicillin-resistant S. aureus (MRSA), and E. faecalis (MIC90 values of 0.25, 2, and 2 mcg/mL). Ceftobiprole has also demonstrated potent in vitro activity against several clinical isolates of community-associated Methicillin-resistant S. aureus (CA-MRSA), vancomycin-intermediate S. aureus (VISA), and Vancomycin-resistant S. aureus (VRSA), with a minimum inhibitory concentration (MIC) of 2 mcg/mL [1]. Ceftobiprole is highly active against S. aureus, with MICs ranging from 0.12 to 4 mg/L (only one resistant strain, MIC of 4 mg/L). Furthermore, Ceftobiprole is twice more active on Methicillin-susceptible S. aureus (MSSA) strains with MIC50 and MIC90 of 0.5 mg/L than on MRSA strains with MIC50 and MIC90 of 1 mg/L. Moreover, Panton-Valentine leukocidin (PVL)+MRSA is slightly more susceptible to Ceftobiprole (MIC50: 0.5 mg/L, MIC90: 1 mg/L) than PVL-MRSA (MIC50 and MIC90 of 1 mg/L) [2].

Cas No.

209467-52-7

分子式

C20H22N8O6S2

分子量

534.57

别名

Ro 63-9141;BAL 9141;头孢吡普;Ceftobiprole

储存和溶解度

DMSO:5 mg/mL (9.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years