Colistin adjuvant-1 是一种粘菌素佐剂 (colistin adjuvant),对革兰氏阴性细菌显示出增强的粘菌素增强活性。Colistin adjuvant-1 抑制NF-Κb的IC50为 0.209 μM。
产品描述
Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC 50 of 0.209 μM [1].
体外活性
Colistin adjuvant-1 (compound 13) inhibits a panel of additional colistin-resistant strains of K. pneumoniae and A. baumannii, including strains harboring the mcr-1 gene, and also determined activity against colistin-resistant strains of P. aeruginosa [1].
分子式
C16H7F9N2O
分子量
414.23
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years