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Fluphenazine decanoate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fluphenazine decanoate图片
CAS NO:5002-47-1
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
Fluphenazine decanoate 是一种高度连续的多巴胺D2受体阻滞剂,是一种长效吩噻嗪抗精神病药,用于精神分裂症的研究。

产品描述

Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia.

体内活性

Six female Persian onagers (Equus hemionus onager) were treated with fluphenazine decanoate (FD;?0.1?mg/kg IM) or saline control in a random crossover design study.?Urinary cortisol, progesterone, estrogen metabolites and behavior were monitored, and follicular dynamics were examined using ultrasonography until ovulation.?Onagers demonstrated significantly lower cortisol concentrations (P?=?0.03) when treated with FD (6.61?±?3.26?ng/mg creatinine) compared to saline (9.73?±?3.19?ng/mg creatinine).?Overall, there were no differences in peak estrogen (P?=?0.51) or progesterone (P?=?0.38) concentrations between the two groups, and all animals ovulated within the expected time frame following FD treatment.?However, some onagers exhibited only minor reductions in cortisol secretion and one treated female demonstrated a suppressed luteal progesterone peak, indicating a possible reproductive cost to FD administration[1].

Cas No.

5002-47-1

分子式

C32H44F3N3O2S

分子量

591.77

别名

Fluphenazine decanoate

储存和溶解度

DMSO:125 mg/mL (211.23 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years