您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > L-Cysteinesulfinic acid monohydrate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
L-Cysteinesulfinic acid monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Cysteinesulfinic acid monohydrate图片
CAS NO:207121-48-0
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品介绍
L-Cysteinesulfinic acid monohydrate 是代谢型谷氨酸受体 (mGluRs) 的有效激动剂,可以作用于 mGluR1,mGluR2,mGluR5,mGluR4,mGluR6 和 mGluR8,pEC50分别为 3.92,3.9,4.6,2.7,4.0,和 3.94。

产品描述

L-Cysteinesulfinic acid monohydrate is a potent agonist at rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively[1].

体外活性

L-Cysteinesulfinic acid (monohydrate) is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA (monohydrate) is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA (monohydrate) selectively activates the PLD-coupled receptor. 1 mM L-CSA (monohydrate) induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA (monohydrate) elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC50 of 500 uM. The PLD response induced by 1 mM L-CSA (monohydrate) is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA (monohydrate)-induced increases in cell firing[1].

Cas No.

207121-48-0

分子式

C3H9NO5S

分子量

171.17

别名

L-Cysteinesulfinic acid monohydrate

储存和溶解度

H2O:120 mg/mL (701.06 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years