产品描述
ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). It inhibits food consumption in nonfasted mice without affecting motor activity. ABD459 reduces active food seeking for 5-6 hours after treatment, with no rebound after washout. ABD459 also diminishes rapid eye movement (REM) sleep, with no alterations of wakefulness or non-REM sleep.
Cas No.
1047670-51-8
分子式
C24H17BrCl2N2O2
分子量
516.21
别名
ABD459
储存和溶解度
DMF:3 mg/mL
DMF:PBS(pH7.2) (1:2):0.33 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years