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Zamifenacin fumarate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Zamifenacin fumarate图片
CAS NO:127308-98-9
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
扎非那星富马酸盐
UK-76654 fumarate
产品介绍
Zamifenacin fumarate 是肠道选择性毒蕈碱M3受体的有效拮抗剂, 可显著降低肠易激综合症的结肠蠕动。

产品描述

Zamifenacin fumarate is a potent and gut-selective antagonist of muscarinic M3 receptor.

体内活性

Zamifenacin exhibits terminal elimination half-lives (mouse 2.1, rat 6.0 and, dog 1.1 h) due to high plasma clearance (68, 35, and 39 mL/min/kg respectively combined with large volumes of distribution (12.5, 19.0, and 3.5 L/kg respectively) following intravenous administration (mouse 5.3, rat 5.0 and, dog 1.0 mg/kg)[2].

Cas No.

127308-98-9

分子式

C31H33NO7

分子量

531.6

别名

扎非那星富马酸盐;UK-76654 fumarate;Zamifenacin fumarate

储存和溶解度

H2O:1 mg/mL (1.88 mM),Need ultrasonic and warming and heat to 60°C
DMSO:55 mg/ml (103.46 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years