(R,R)-CXCR2-IN-2, diastereoisomer of CXCR2-IN-2 (compound 68), is a brain penetrant CXCR2 antagonist with a pIC50 of 9 and 6.8 in the Tango assay and d in the HWB Gro-α induced CD11b expression assay, respectively[1].

1838123-22-0

C18H23ClN2O5S

414.9

(R,R)-CXCR2-IN-2;(R,R)-CXCR2-IN-2

DMSO:220 mg/mL (530.25 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years