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NO-prednisolone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NO-prednisolone图片
CAS NO:327610-87-7
包装:25 mg
市场价:10957元

产品名称
NCX-1015
NO-泼尼松龙
产品介绍

产品描述

NO-prednisolone is a potently stimulates IL-10 production in vivo, and isnitric oxide (NO)-releasing derivative of Prednisolone.

体外活性

lipopolysaccharide induced interleukin-1 beta release from these cells was inhibited by NCX-1015 with higher potency than prednisolone.

体内活性

In a chronic model of granulomatous tissue inflammation, administration of NCX-1015 (13.9 micromol kg(-1)) from day 1 (i.e. after induction of inflammation) was more effective than prednisolone in reducing the granuloma dry weight, and this was associated to a lower anti-angiogenic effect.

Cas No.

327610-87-7

分子式

C29H33NO9

分子量

539.57

别名

NCX-1015;NO-泼尼松龙;NO-prednisolone

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years