Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity.

63775-95-1

C61H109N11O12

1188.58

Antibiotic S 7481F2;7-L-Alanine-cyclosporin A;Cyclosporin B

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years