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Arecaidine propargyl ester(hydrobromide)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arecaidine propargyl ester(hydrobromide)图片
CAS NO:116511-28-5
包装:200 mg
市场价:9444元

产品名称
Arecaidine propargyl ester (hydrobromide)
产品介绍

产品描述

Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 μM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 μM.2Arecaidine propargyl ester decreases mean arterial blood pressure in normotensive cats (ED25= 1.9 nmol/kg).3It is toxic to house flies (Musca) when administered at a dose of 75 μg/fly.4

Cas No.

116511-28-5

分子式

C10H14BrNO2

分子量

260.13

别名

Arecaidine propargyl ester (hydrobromide)

储存和溶解度

PBS (pH 7.2):10 mg/mL
DMSO:30 mg/mL
DMF:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years