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7-Methoxyflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Methoxyflavone图片
CAS NO:22395-22-8
包装与价格:
包装价格(元)
100 mg电议
1 mL*10 mM(in DMSO)电议

产品介绍
7-Methoxyflavone 是一种分离自 Zornia brasiliensis 的化合物。它能够抑制福尔马林疼痛反应神经源期的舔爪时间 (65.6%),有外周镇痛活性,但不影响炎症期的伤害性反映。

产品描述

7-Methoxyflavone isolated from Zornia brasiliensis with antinociceptive effects.

体内活性

The antinociceptive effect of 7-methoxyflavone (7MF) in mice using the following tests: acetic acid-induced writhing, glutamate- and formalin-induced nociception and hotplate. 7MF (30, 50, 100 and 300 μmol/kg, i.p.) reduced the number of writhes, with ID?? = 82.5 ± 11.7 μmol/kg and E max = 58.4%. 7MF treatment (100 μmol/kg, i.p.) inhibited paw-licking time in the neurogenic phase of the formalin pain response (65.6%) and did not decrease the nociceptive response in the inflammatory phase. In addition, in glutamate-induced nociception, 7MF inhibited 26% of the nociceptive answer. On the other hand, 7MF did not increase the latency time of the animals in the hotplate test. These results suggest that 7MF has peripheral antinociceptive activity

Cas No.

22395-22-8

分子式

C16H12O3

分子量

252.26

别名

7-Methoxyflavone

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years