Cefathiamidine 是一种头孢菌素抗菌剂，可研究由易感细菌引起的感染，还可用于呼吸道、肝脏、五官感觉、尿路感染以及心内膜炎和败血症的研究。

Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis

All the 56 strains of Str. faecalis tested were inhibited by 2 mg/l of cefathiamidine.?MICs of ampicillin were twofold higher than those of cefathiamidine and MICs of cephaloridine and cephazolin were 8-16-fold higher.?No significant inoculum effect on MICs of cefathiamidine could be seen.?Two isolates of Str. faecium showed resistance to the four antibiotics.?The MBCs of cefathiamidine and ampicillin for ten strains of Str. faecalis showed that the ratios of MBC/MIC were greater than 64.?The rates of killing of Str. faecalis were reduced at concentrations of cefathiamidine and ampicillin greater than the MIC.?The most rapid killing was obtained at 2 mg/l cefathiamidine or 4 mg/l of ampicillin.?With the addition of 1 mg/l gentamicin this paradoxical bacteriocidal effect was eliminated[1].

33075-00-2

C19H28N4O6S2

472.58

Cefathiamidine

DMSO:250 mg/mL (529.01 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years