COX-2-IN-9 (compound 7a) 是一种有效的、选择性的、具有口服活性的COX-2抑制剂,具有IC5010.17 uM。COX-2-IN-9 的 COX-2 选择性高于 CeleCOXib。COX-2-IN-9 具有良好的体内抗炎活性和低致溃疡活性。
产品描述
COX-2-IN-9 (compound 7a) is a potent, selective, and orally active inhibitor of COX-2 with an IC 50 of 10.17 uM. COX-2-IN-9 has higher COX-2 selectivity than Celecoxib. COX-2-IN-9 shows good in vivo anti-inflammatory and low ulcerogenic activity [1].
分子式
C25H23N5O4S2
分子量
521.61
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years