COX-2-IN-7 (compound 4a) 是一种有效的、选择性的、具有口服活性的COX-2抑制剂,具有IC506.585 uM。COX-2-IN-7 的 COX-2 选择性高于 CeleCOXib。COX-2-IN-7 具有良好的体内抗炎活性和低致溃疡活性。
产品描述
COX-2-IN-7 (compound 4a) is a potent, selective, and orally active inhibitor of COX-2 with an IC 50 of 6.585 uM. COX-2-IN-7 has higher COX-2 selectivity than Celecoxib. COX-2-IN-7 shows good in vivo anti-inflammatory and low ulcerogenic activity [1].
分子式
C15H13N3O2S2
分子量
331.41
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years