您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > tetranor-PGDM
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
tetranor-PGDM
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
tetranor-PGDM图片
CAS NO:70803-91-7
包装:1 mg
市场价:-1元

产品介绍

产品描述

Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. PGD2 is also produced in the brain by lipocalin-PGD-synthase also known as β-trace. In the brain, PGD2 produces normal physiological sleep and lowering of body temperature. Further pharmacological actions include inhibition of platelet aggregation and relaxation of vascular smooth muscle. tetranor-PGDM is a major metabolite of PGD2 that is detectable in human and mouse urine. The levels of tetranor-PGDM and 2,3-dinor-11β-PGF2α , a related PGD2 metabolite, in human urine were found to be 1.5 ± 0.3 and 0.6 ± ng/mg creatinine, respectively. tetranor-PGDM was detected in murine urine at a level of 8.1 ± 1.3 ng/mg creatinine.

Cas No.

70803-91-7

分子式

C16H24O7

分子量

328.36

别名

tetranor-PGDM

储存和溶解度

DMF:50 mg/mL
DMSO:50 mg/mL
PBS (pH 7.2):1 mg/mL
Ethanol:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years