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Biperiden Hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biperiden Hydrochloride图片
CAS NO:1235-82-1
包装:100 mg
市场价:10317元

产品名称
KL 373 (Hydrochloride)
盐酸比哌立登
产品介绍

产品描述

Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker and it is used for the adjunctive treatment of all forms of Parkinson's disease (postencephalitic, idiopathic, and arteriosclerotic)[1]. Target: M1 receptors Biperiden is an antiparkinsonian agent of the anticholinergic type. Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervate and it also has a prominent central blocking effect on M1 receptors[2]. Biperiden (0.11 mg/kg), benactyzine (0.3 mg/kg),caramiphen (10 mg/kg), procyclidine (3 mg/kg), and trihexyphenidyl (0.12 mg/kg) separately and each in combination with physostigmine (0.1 mg/kg) is to make a comparative assessment of potential cognitive effects. The results showed that benactyzine, caramiphen, and trihexyphenidyl reduced rats' innate preference for novelty. Whereas biperiden and procyclidine did not [3]. Clinical indications: parkinsonism FDA Approved Date: Toxicity: Drowsiness; vertigo; headache; dizziness

Cas No.

1235-82-1

分子式

C21H30ClNO

分子量

347.92

别名

KL 373 (Hydrochloride);盐酸比哌立登;Biperiden Hydrochloride

储存和溶解度

H2O:5 mg/mL (14.37 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years