Streptazolin is a fungal metabolite originally isolated from S. virIDOchromogenes. It increases NF-Κb activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.

Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes. It increases NF-κB activity when used at concentrations ranging from 60 to 130 μg/ml, at least in part, via PI3K signaling. Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.

80152-07-4

C11H13NO3

207.229

Streptazolin

Ethanol:Soluble
Dichloromethane:Soluble
Methanol:Soluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years