产品描述
KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 μM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion injury.
Cas No.
852146-73-7
分子式
C13H12FN3O2
分子量
261.256
别名
KR-32568
储存和溶解度
DMSO:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years