产品描述
STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 .
Cas No.
652142-94-4
分子式
C19H11Cl2N5O
分子量
396.23
别名
STING Agonist 1a
储存和溶解度
DMSO:Slightly soluble
PBS (pH 7.2):Slightly soluble
DMF:Slightly soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years