NLRP3-IN-11 是一种NLRP3蛋白抑制剂。NLRP3-IN-11 具有生物活性,IC50值<0.3 μM。NLRP3-IN-11 可用于炎症和退行性疾病的研究,包括 NASH、动脉粥样硬化和其他心血管疾病、阿尔茨海默病、帕金森病、糖尿病、痛风和许多其他自身炎症性疾病。
产品描述
NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC 50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases [1].
体外活性
NLRP3-IN-11 has biological activity with an IC 50 value of <0.3 μM in human PBMC NLRP3 assay [1]
Cas No.
2769040-91-5
分子式
C17H17ClN4O2
分子量
344.8
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years