Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. Cell permeable.

1435893-78-9

C50H88N14O15

1125.33

NoxA1ds

H2O:2 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years