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(Rac)-Idroxioleic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(Rac)-Idroxioleic acid图片
CAS NO:56472-29-8
包装与价格:
包装价格(元)
1 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
2-羟基乳清酸
Minerval
2-Hydroxyoleic acid
2-OHOA
产品介绍
(Rac)-Idroxioleic acid 是一种具有抗肿瘤作用的脂肪酸酰胺水解酶抑制剂。 它与质膜结合并改变脂质组织。

产品描述

Minerval is a fatty acid amide hydrolase inhibitor with anti-tumor effect. It binds to the plasma membrane and alters lipid organization.

体外活性

Minerval (25-50 μM; 72 hours) causes a marked and concentration-dependent increase in the proteolytic cleavage of PARP, a molecular marker of apoptosis. Minerval (25-75 μM; 72 hours) impairs Jurkat cell growth in a time- and concentration-dependent manner (IC50: 40 μM)[1].

体内活性

In nude mice infected with Jurkat cells, Minerval significantly inhibits tumour growth[1].

Cas No.

56472-29-8

分子式

C18H34O3

分子量

298.46

别名

2-羟基乳清酸;Minerval;2-Hydroxyoleic acid;2-OHOA;(Rac)-Idroxioleic acid

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years