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ML67-33
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ML67-33图片
CAS NO:1443290-89-8
包装:25 mg
市场价:7202元

产品介绍

产品描述

ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) (EC50s: 36.3 μM and 9.7 μM in cell-free and HEK293 cells, respectively). ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.

体外活性

ML67-33 activates K2P channels and mutants. It has an EC50s of 21.8±1.3 μM, 49.4±1.1 μM, 30.2±1.4 μM, and 27.3±1.2 μM for K2P2.1 (TREK-1) W275S, K2P2.1 (TREK-1)-3G, K2P10.1 (TREK-2), K2P4.1 (TRAAK), respectively.

Cas No.

1443290-89-8

分子式

C18H17Cl2N5

分子量

374.27

别名

ML67-33

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years