产品描述
EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
Cas No.
676657-00-4
分子式
C74H108N14O17
分子量
1465.75
别名
KYL;KYL peptide
储存和溶解度
H2O:2 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years