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Substance P(1-7)2TFA(68060-49-1(free base))
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Substance P(1-7)2TFA(68060-49-1(free base))图片
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
Substance P (1-7) 2TFA(68060-49-1(free base))
产品介绍
Substance P (1-7) 2TFA(68060-49-1(free base)) 是速激肽P(SP)蛋白水解降解后形成的主要生物活性代谢物,具有抗炎、抗伤害和抗痛觉过敏作用。

产品描述

Substance P (1-7) 2TFA(68060-49-1(free base)) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects

体内活性

Substance P 1-7, SP(1-7), which is the main SP fragment in rat CNS, was injected intranigrally. SP(1-7) was found to act as a very potent antagonist against the SP-induced responses and was formed locally in the nigra after SP injection. It is proposed that SP(1-7) is an endogenous modulator of SP actions. Generation of peptide fragments, which retain receptor affinity but not efficacy, may be a general mechanism for autoregulation in peptidergic systems[1].

Cas No.

T7675

分子式

C45H67F6N13O14

分子量

1128.08

别名

Substance P (1-7) 2TFA(68060-49-1(free base))

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years