您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > PGD2-IN-1
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PGD2-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PGD2-IN-1图片
CAS NO:885066-67-1
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
PGD2-inhibitor
产品介绍
PGD2-inhibitor 是DP受体拮抗剂(IC50:0.3 nM),摘自专利 WO 2006044732 A2,化合物实例 15 (d)。

产品描述

PGD2-IN-1 is an antagonist of DP extracted from patent WO 2006044732 A2, example 15 (d)

体外活性

Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists have been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically have been shown to inhibit the antigen-induced nasal congestion.

Cas No.

885066-67-1

分子式

C23H23Cl2N3O3

分子量

460.36

别名

PGD2-inhibitor;PGD2-IN-1

储存和溶解度

DMSO:25 mg/mL (54.31 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years