TCMDC-125457 在诱导钙再分布方面有效,但对血红素结晶的抑制作用最小。单剂量TCMDC-125457与青蒿琥酯联合使用时,对紧密同步的青蒿素耐药环期寄生虫具有很高的疗效。
产品描述
TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites.
Cas No.
872113-12-7
分子式
C19H18ClN5O3
分子量
399.84
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years