Endogenous APJ receptor agonist that is secreted by adipocytes. Binds with high affinity to APJ receptors (IC50 = 5.4 nM) and potently inhibits cAMP production in vitro (EC50 = 0.52 nM). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

230299-95-3

C185H304N68O43S

4200.93

Apelin-36 (rat, mouse);Apelin-36(rat, mouse)

H2O:1.60 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years