ATX inhibitor 11 (compound 13c) 是一种有效的ATX(autotaxin) 抑制剂，其IC50为 2.7 nM。在小鼠纤维化模型中，ATX inhibitor 11 可缓解纤维化组织的严重程度，有效减少纤维化生物标志物 α-SMA 的沉积。ATX inhibitor 11 可用于肺纤维化研究。

ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC 50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research [1].

2485779-27-7

C32H35N5O6

585.65

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years