C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂,一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
产品描述
C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin.
体外活性
In CHO cells expressing human NPR-B, C-Type Natriuretic Peptide (CNP) (1-22), human acetate (0.01, 0.1, 1, 10, 100, 1000 nM) increased cGMP production in a concentration-dependent manner[2].
体内活性
C-Type Natriuretic Peptide (CNP) (1-22), human acetate (2 nM; i.c.v.) induced an increase in the severity of picrotoxin-kindled convulsions 24 hours after application of the peptide[3].
Cas No.
T39392L
分子式
C97H162F3N27O32S3
分子量
2371.68
别名
C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base);C-Type Natriuretic Peptide (CNP) (1-22), human acetate
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years