FLT3/ITD-IN-1 (Compound 1) 是一种有效的FLT3-ITD抑制剂，对FLT3和 FLT3-ITD 的IC50值分别为 38.2 nM 和 144.1 nM。FLT3/ITD-IN-1 对急性髓系白血病细胞具有良好的抗增殖活性。

FLT3/ITD-IN-1 (Compound 1) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 38.2 nM and 144.1 nM against FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-1 displays excellent antiproliferative activities against acute myeloid leukemia cell lines [1].

C19H22N6O2

366.42

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years