L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine.

In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism. Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.

1431868-11-9

C15H11I4NO4

786.8

L-Thyroxine-13C9,15N;L-Thyroxine-13C9,15N

DMF:0.14 mg/mL
DMSO:2.5 mg/mL
DMSO:PBS (pH 7.2) (1:1):0.50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years