Necroptosis-IN-3(Compound 69) 是一种坏死性凋亡 (necroptosis) 抑制剂,抑制 TNF-α 诱导的坏死性凋亡。Necroptosis-IN-3(Compound 69) 也抑制 11β-HSD1。
产品描述
Necroptosis-IN-3 (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
体外活性
TNF-α-IN-8 (Compound 69) (0.030-100 μ M; 24 h) inhibits TNF-α induced necrosis of human Jurkat T cells with FADD deficiency [1].
Cas No.
547698-18-0
分子式
C12H17NOS
分子量
223.33
别名
Cyclohexanecarboxamide, N-(2-thienylmethyl)-;Necroptosis-IN-3
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years