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Necrostatin-5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Necrostatin-5图片
CAS NO:337349-54-9
包装:200 mg
市场价:7973元

产品介绍

产品描述

Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligand-induced and tumor necrosis factor-α (TNF-α) induced necrosis. Necrostatin-5 is a selective allosteric inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells with an EC50 value of 240 nM.

Cas No.

337349-54-9

分子式

C19H17N3O2S2

分子量

383.49

别名

Necrostatin-5

储存和溶解度

DMSO:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years