RIPK1-IN-12 是一种有效的RIPK1抑制剂，RIPK1-IN-12 能抑制人和小鼠细胞的坏死性凋亡，EC50值分别为 1.6 和 2.9 nM.

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC 50 values of 1.6 and 2.9 nM, respectively [1].

RIPK1-IN-12 (Compound 58; 24 hours) demonstrates potent anti-necroptotic activity (EC 50 =1.6 nM in HT-29 cells and EC 50 = 2.9 nM in L929 cells) [1].

2173556-92-6

C24H26N4O3S

450.55

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years