RIPK1-IN-14 (Compound 41) 是一种有效的RIPK1抑制剂,IC50值为 92 nM。RIPK1-IN-14 在 U937 细胞的坏死性凋亡模型中显示出显着的抗坏死性凋亡作用。
产品描述
RIPK1-IN-14 (Compound 41) is a potent inhibitor of RIPK1 with an IC 50 value of 92 nM. RIPK1-IN-14 shows a significant anti-necroptotic effect in a necroptosis model in U937 cells [1].
分子式
C25H25F2N3O2
分子量
437.48
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years