C14 Ceramide is an endogenous ceramide generated by ceramide synthase 6. [1] During nutrient-deprivation-induced necroptosis in MEF cells, C14 ceramide levels increase in a time-dependent manner. [2] C14 ceramide plasma levels were reduced in obese patients with or without diabetes following a 12-week supervised exercise training program, correlating positively with weight and fat loss and negatively with an increase in insulin sensitivity. [3] In contrast, plasma levels were higher in Parkinson's disease patients with dementia than those without dementia and higher levels were correlated with deficits in memory.[4]

34227-72-0

C32H63NO3

509.85

Cer(d18:1/14:0);C14 Ceramide (d18:1/14:0)

DMF:0.15 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years