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JBJ-03-142-02
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
JBJ-03-142-02图片
CAS NO:2068806-31-3
包装:50 mg
市场价:8090元

产品介绍

产品描述

Highly potent epidermal growth factor receptor (EGFR) and ErbB2 (human epidermal growth factor receptor; HER2) inhibitor. Inhibits wild type and tumorgenic mutated receptors (exon 20 insertion; Ex20Ins). Antiproliferative in vitro (IC50 values are 7.6, 30 - 95, 3.8 and 19 - 31 nM for Ba/F3 cells expressing wild type EGFR, EGFR with Ex20Ins mutation, wild type HER2 and HER2 with Ex20Ins mutation, respectively). Also inhibits other common EGFR mutants. Antiproliferative in patient-derived lung cancer cell lines.

Cas No.

2068806-31-3

分子式

C25H22FN7O3

分子量

487.49

别名

JBJ-03-142-02

储存和溶解度

DMSO:24.37 mg/mL(50 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years