cRIPGBM 是RIPGBM 的促凋亡衍生物。cRIPGBM通过与受体相互作用蛋白激酶2(RIPK2)结合，从而选择性诱导 GBM 肿瘤干细胞凋亡，对 GBM-1 细胞的EC50值为 68 nM。

cRIPGBM is a proapoptotic derivative of RIPGBM. cRIPGBM is a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC 50 of 68 nM in GBM-1 cells [1].

2361988-76-1

C26H20FN2O2+

411.45

cRIPGBM

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years