Chelidonine hydrochloride是 Chelidonium majus 的生物碱之一，具有广泛的药理活性。

Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities

Chelidonine significantly suppressed LPS-induced the production of NO and PGE2, as well as iNOS and COX-2 mRNA and protein expression.?In addition, pro-inflammatory cytokines induced by LPS, such as TNFα and IL-6 were also attenuated by chelidonine.?What's more, LPS-induced activation and degradation of IκBα followed by translocation of the p65 from the cytoplasm to the nucleus were attenuated by chelidonine.?Furthermore, chelidonine even significantly inhibited TLR4 expression induced by LPS[1].

4312-31-6

C20H20ClNO5

389.83

Chelidonine hydrochloride

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years