VU 0365114 是 mAChR M5 的正变构调节剂，可增加 ACh 诱导的钙动员，EC50为 2.7 μM。

VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).

1208222-39-2

C22H14F3NO3

397.35

VU 0365114

H2O:< 0.1 mg/mL (insoluble)
DMSO:50 mg/mL (125.83 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years