Omigapil maleate 是一种口服有效的 GAPDH 亚硝基化抑制剂，可消除 Aβ1-42 诱导的小鼠 tau 乙酰化，记忆障碍和运动功能障碍，Omigapil maleate 具有研究阿尔茨海默症的潜力。Omigapil maleate (CGP3446B maleate) 是一种有效的Apoptosis" style="display: inline; color: #c13a36">凋亡 (Apoptosis) 抑制剂。Omigapil maleate 可用于研究先天性肌营养不良 (CMD)。

Omigapil maleate is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).

Treatment with Omigapil (0.1 mg/kg) in 12-week-old dyW/ mag mice results in improved muscle regeneration and increased force [2].

200189-97-5

C23H21NO5

391.42

Omigapil (Maleate);马来酸CGP3466B;Omigapil maleate;CGP 3466B maleate

DMSO:40 mg/mL (102.2 mM),ultrasonic and warming and heat to 80°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years