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Amyloid-β(25-35)Peptide(human)(trifluoroacetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amyloid-β(25-35)Peptide(human)(trifluoroacetate salt)图片
包装:1 mg
市场价:1232元

产品名称
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
产品介绍

产品描述

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.

体内活性

In vivo, intracerebral injection of Aβ (25-35) (20 nmol) in rats induces lesions of neuronal and tissue loss. Aggregated Aβ (25-35) administered intracerebroventricularly to rats induces learning and memory impairments in the Y-maze, novel object recognition, and contextual fear conditioning tests.

别名

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

储存和溶解度

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years