GOT1 inhibitor-1 是一种新型的、非共价的谷氨酸草酰乙酸转氨酶 1 (GOT1) 抑制剂(IC50:8.2 uM),是一种戊酸衍生物。 它可用于以及胰腺导管腺癌 (PDAC) 。
产品描述
GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
体外活性
In the MDH coupled GOT1 enzymatic assay, GOT1 inhibitor-1 shows an inhibitory effect on GOT1 activity with an IC50 of 8.2 μM[1].
Cas No.
732973-87-4
分子式
C19H19ClN4O
分子量
354.84
别名
GOT1 inhibitor 2c;GOT1 inhibitor-1
储存和溶解度
DMSO:120mg/ml(338.19mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years