Bis(7)-tacrine dihydrochloride 衍生自tacrine ,是一种二聚体乙酰胆碱酯酶 (AChE) 抑制剂,具有治疗阿尔茨海默病的潜力。Bis(7)-tacrine dihydrochloride 通过阻断 NMDA 受体防止谷氨酸诱导的神经元凋亡。Bis(7)-tacrine dihydrochloride 是一种有效的GABAA受体拮抗剂。
产品描述
Bis(7)-tacrine dihydrochloride is a dimeric AChE inhibitor derived from tacrine with a potential to treat Alzheimer's disease. Bis(7)-tacrine dihydrochloride prevents glutamate-induced neuronal apoptosis by blocking NMDA receptors. Bis(7)-tacrine dihydrochloride is a potent GABA A receptor antagonist[1] [2] [3].
Cas No.
224445-12-9
分子式
C33H42Cl2N4
分子量
565.62
别名
bis(7)-Tacrine
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years