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7-Chlorokynurenic acid sodium salt
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Chlorokynurenic acid sodium salt图片
CAS NO:1263094-00-3
包装:200 mg
市场价:8321元

产品名称
7-CKA sodium salt
产品介绍

产品描述

7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles (Ki: 0.59 μM).

体内活性

Male Sprague-Dawley rats pretreated with 7-Chlorokynurenic acid sodium salt (10 nM) shows significant retardation of the development of both the electroencephalographic and motor (17.7±2.9 daily stimulations) components of the seizure response [3].

Cas No.

1263094-00-3

分子式

C10H6ClNNaO3

分子量

246.6

别名

7-CKA sodium salt;7-Chlorokynurenic acid sodium salt

储存和溶解度

H2O:50 mg/mL (203.59 mM),Need ultrasonic
DMSO:33.67 mg/mL (137.10 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years