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N-(α-Linolenoyl)Tyrosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
N-(α-Linolenoyl)Tyrosine图片
CAS NO:259143-19-6
包装:100 mg
市场价:10826元

产品名称
N-(α-Linolenoyl) Tyrosine
产品介绍

产品描述

Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons. N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier. In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson's therapeutic agent.

Cas No.

259143-19-6

分子式

C27H39NO4

分子量

441.6

别名

N-(α-Linolenoyl) Tyrosine

储存和溶解度

DMF:30 mg/mL
DMSO:30 mg/mL
PBS (pH 7.2):1 mg/mL
Ethanol:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years