Topoisomerase I inhibitor 7 (Compound 8) 是一种有效的Topoisomerase I抑制剂。Topoisomerase I inhibitor 7 显着抑制肿瘤生长(高达 79%)并延长接受 P388 淋巴瘤移植的小鼠的寿命(153%)。Topoisomerase I inhibitor 7 表明了在杂芳烃融合蒽醌类中进一步寻找新的抗肿瘤候选药物的前景。
产品描述
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor drug candidates among the heteroarene-fused anthraquinones [1].
Cas No.
2408639-81-4
分子式
C22H19N3O5
分子量
405.4
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years